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Cytokines: Classification, Receptors, and Functions

Cytokines: Classification, Receptors, and Functions

Paperback

Biology

ISBN10: 6630274482
ISBN13: 9786630274486
Publisher: Scholars' Press
Published: Jul 27 2026
Pages: 76
Weight: 0.25
Height: 0.18 Width: 6.00 Depth: 9.00
Language: English
Cytokines are small, low-molecular-weight regulatory proteins that coordinate immune and inflammatory responses by mediating communication among immune and non-immune cells. They are classified as pro-inflammatory, anti-inflammatory, or pleiotropic based on their biological functions. Cytokines act through specific cell-surface receptors, activating signaling pathways such as JAK/STAT, NF-κB, MAPK, PI3K/AKT, and SMAD to regulate gene expression, cell proliferation, differentiation, and survival. Dysregulated cytokine signaling contributes to the development of autoimmune, inflammatory, infectious, metabolic, cardiovascular, diabetic, and neurodegenerative diseases. Consequently, cytokines and their receptors serve as important biomarkers and therapeutic targets for numerous immune-mediated disorders.

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Hassan, Heba

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Biology