Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Crucial Roles of Autophagy in Cancer Metastasis

Crucial Roles of Autophagy in Cancer Metastasis

Medhat, Dalia

Paperback

Biology

ISBN10: 6209032680
ISBN13: 9786209032684
Publisher: Scholars' Press
Published: Sep 26 2025
Pages: 76
Weight: 0.25
Height: 0.18 Width: 6.00 Depth: 9.00
Language: English
Autophagy is an intracellular degradation system that delivers cytoplasmic components to the lysosome. Despite its apparent simplicity, recent research has revealed that it plays a wide range of physiological and pathophysiological roles, many of which are highly complex. The process of autophagy occurs through several sequential steps-sequestration, transport to lysosomes, degradation, and utilization of degradation products-with each step potentially fulfilling distinct functions. In cancer progression, metastasis represents an especially complex process. Autophagy exerts stage-specific effects: in the early stages, it functions as a tumor suppressor by preventing necrosis and limiting inflammation, whereas in advanced stages, it can promote metastasis by enabling malignant cells to disseminate into the bloodstream. This book explores the mechanisms of autophagy and its role in driving cancer metastasis, with particular attention to how it enhances tumor aggressiveness in a process-dependent manner.

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