Sign-In
Cart
Rewiring Pain: The Neuroscience of How the Brain Unlearns Chronic Pain: A Research-Based Guide to Neuroplasticity, Pain Reprocessing, and What the Sci
Paperback
Series: The Pain Science
Medical ReferencePain Management
Publisher: Independently Published
Published: May 10 2026
Pages: 216
Weight: 0.65
Height: 0.46 Width: 6.00 Depth: 9.00
Language: English
Your brain learned chronic pain. The same brain can change it. Here is what the research actually shows.
If you live with chronic pain, you have almost certainly been told one of two things: that the pain is permanent, or that it is the result of damage that cannot be reversed. You have probably read about pain reprocessing therapy, neuroplasticity, and the brain's role in chronic pain, and come away unsure what to believe. Some books promise miracle cures. Some clinicians dismiss the entire field. Neither extreme tells you what the research actually shows.
This book is for the intelligent reader who wants the truth about brain-based pain change, written by a researcher who has followed the literature closely and refuses to overstate or understate what the science says. It is not a self-help programme. It is not a recovery plan. It is a rigorous, honest, and genuinely hopeful explanation of how the brain learns chronic pain, what neuroplasticity means in this specific context, and what the current evidence tells us about the conditions under which a nervous system trained on persistent pain can begin to change.
You will discover what neuroimaging studies show before and after recovery, what the Boulder Back Pain Study actually demonstrated, how graded motor imagery and pain neuroscience education work at a neurological level, and why interoception is central to the mechanism of change rather than a relaxation technique. You will also find a clinically precise chapter on how opioids, benzodiazepines, and other common pain medications interact with the neuroplastic processes that underlie recovery, equipping you with the research you need to have a more informed conversation with your prescribing clinician.
Inside this book you will learn:
- How the brain learns to produce chronic pain through prediction, fear, and protective behaviour, and why understanding the mechanism is the first step toward changing it
- What neuroplasticity actually means in the context of pain, stripped of wellness clichés and grounded in current neuroscience
- What the leading clinical trials in pain reprocessing therapy have shown, including effect sizes, populations, limitations, and what remains unresolved
- Why interoception, the brain's capacity to read internal body signals, is the specific neurological mechanism through which somatic tracking and pain reprocessing work
- How graded exposure reduces the threat value of movement through prediction error and fear extinction, not simply by pushing through pain
- How benzodiazepines may interfere with fear extinction learning, what the opioid-induced hyperalgesia research reveals, and what the evidence shows about SNRIs and neuroplasticity
- What predicts who responds to brain-based approaches and who does not, and what to do when progress stalls
- What the long-term follow-up data shows about maintaining recovery, navigating setbacks, and the non-linear path most patients actually walk
This is the book to read before, during, or alongside whatever clinical treatment you are pursuing. It will not promise that your pain is reversible. It will give you a clear, evidence-grounded understanding of what is possible, what is uncertain, and why the brain that learned to hurt holds the capacity to change.
Also from
Langford, R. V.
The Pain-Sleep Spiral: How Chronic Pain Destroys Sleep, and How Poor Sleep Makes Pain Worse
Langford, R. V.
Paperback
An Introduction to Phenomenology: Experience, Consciousness, and What It Is Like to Be
Langford, R. V.
Paperback
Anxious Attachment: The Psychology of Why You Fear Abandonment and How to Build Genuine Security
Langford, R. V.
Paperback
Attachment and the Brain: The Neuroscience of Love, Loss, and Why Relationships Rewire Us
Langford, R. V.
Paperback
Avoidant Attachment: Why You Pull Away From Closeness and What the Research Says About Changing It
Langford, R. V.
Paperback
Attachment in Parenting: How the Bond You Received Shapes the Parent You Become
Langford, R. V.
Paperback
Pain and the Past: How Adverse Experiences Rewire the Nervous System and Amplify Physical Suffering
Langford, R. V.
Paperback
Pelvic Pain and the Nervous System: A Research-Based Explanation of Why It Hurts
Langford, R. V.
Paperback
Hypermobile and Hurting: The Research-Based Guide to EDS, Hypermobility, and Chronic Pain
Langford, R. V.
Paperback
The Pain Brain: What Neuroscience Now Knows About Chronic Pain and Why That Changes Everything
Langford, R. V.
Paperback
Also in
Pain Management
Unlearn Your Pain: The Science of Recovering from Chronic Pain, Fatigue, Anxiety, and Depression
Schubiner, Howard, MD
Hardcover
The Way Out: A Revolutionary, Scientifically Proven Approach to Healing Chronic Pain
Gordon, Alan
Ziv, Alon
Paperback
Mayo Clinic Guide to Arthritis, Revised and Updated: Managing Joint Pain for an Active Life
Arment, Courtney A.
Hardcover
Rebuilding Milo: A Lifter's Guide to Fixing Common Injuries and Building a Strong Foundation for Enhancing Performance
Sonthana, Kevin
Horschig, Aaron
Hardcover
Shoulder Pain? The Solution & Prevention: Fifth Edition, Revised & Expanded
Kirsch, John M.
Paperback
Mind Your Body: A Revolutionary Program to Release Chronic Pain and Anxiety
Sachs, Nicole J., Lcsw
Hardcover
Change Your Brain, Change Your Pain: Breaking the Doom Loop to Heal Chronic Physical and Emotional Pain
Amen, Daniel G.
Hardcover
Becoming a Supple Leopard, 2nd Edition: The Ultimate Guide to Resolving Pain, Preventing Injury, and Optimizing Athletic Performance
Starrett, Kelly
Cordoza, Glen
Hardcover
The Pain Reprocessing Therapy Workbook: Using the Brain's Neuroplasticity to Break the Cycle of Chronic Pain
Sinaiko, Olivia S.
Blackstone, Vanessa M.
Paperback
The Pain Management Workbook: Powerful CBT and Mindfulness Skills to Take Control of Pain and Reclaim Your Life
Zoffness, Rachel
Paperback
The Miracle Ball Method, Revised Edition: Relieve Your Pain, Reshape Your Body, Reduce Your Stress
Petrone, Elaine
Paperback
Pain Free (Revised and Updated Second Edition): A Revolutionary Method for Stopping Chronic Pain
Egoscue, Pete
Paperback
The Pain-Free Body: Simple Stretches and Exercises for Common Aches and Pains
Ginader, Daniel
Paperback
The Trigger Point Therapy Workbook: Your Self-Treatment Guide for Pain Relief
Davies, Clair
Davies, Amber
Paperback
Heal Your Headache: The 1-2-3 Program for Taking Charge of Your Pain
Buchholz, David, M. D.
Paperback
Rehab Science: Back and Spine: Protocols and Exercise Programs for Overcoming Pain and Healing from Injury
Walters, Tom
Cordoza, Glen
Paperback
The Roll Model: A Step-By-Step Guide to Erase Pain, Improve Mobility, and Live Better in Your Body
Miller, Jill
Paperback
Farmacologie Van Dmso: Veilige protocollen, verdunningsmethoden en therapeutische toepassingen voor pijn en ontsteking
Hutsell, Galen
Paperback
Trigger Point Therapy for Myofascial Pain: The Practice of Informed Touch
Finando, Donna
Finando, Steven
Paperback
The Injury Guide: Eliminate Pain, Heal Your Injuries, and Keep Moving Forever
Boynton, Erin, MD
Paperback
Toxic Superfoods: How Oxalate Overload Is Making You Sick--And How to Get Better
Norton, Sally K.
Paperback
The Nervous System Reset: Heal Trauma, Resolve Chronic Pain, and Regulate Your Emotions with the Power of the Vagus Nerve
Maguire, Jessica
Hardcover
Train Your Brain to Beat Chronic Pain: How to Harness the Power of the Mind-Body Connection
Hunt, Carly
Paperback
Rehab Science: Knee: Protocols and Exercise Programs for Overcoming Pain and Healing from Injury
Cordoza, Glen
Walters, Tom
Paperback
The Chronic Illness Workbook: Strategies and Solutions for Taking Back Your Life
Fennell, Patricia A.
Paperback
Rehab Science: Shoulder: Protocols and Exercise Programs for Overcoming Pain and Healing from Injury
Walters, Tom
Cordoza, Glen
Paperback
Power Tools for Health: How pulsed magnetic fields (PEMFs) help you
Msc, William Pawluk
Layne, Caitlin
Paperback
Mindfulness and Self-Compassion for Chronic Pain: A Doctor's Prescription for Natural Pain Relief
Wolf, Christiane
Paperback
Living Well with POTS, MCAS, and EDS: Evidence-Based Solutions for Managing Postural Orthostatic Tachycardia Syndrome, Mast Cell Activation Syndrome,
Kaufman, Stella Marion
Paperback
The Nervous System Reset: Heal Trauma, Resolve Chronic Pain, and Regulate Your Emotions with the Power of the Vagus Nerve
Maguire, Jessica
Paperback
Pain-Free Performance: Move Better, Train Smarter, and Build an Unbreakable Body
Rusin, John
Cordoza, Glen
Hardcover
Make Movement Your Medicine: Gentle Exercises to Soothe and Revive Your Upper Back, Neck and Shoulders
Breakspear, Rachel
Breakspear, Andy
Paperback
Train Your Brain to Beat Chronic Pain: How to Harness the Power of the Mind-Body Connection
Hunt, Carly
Hardcover
Rehab Science: Hip: Protocols and Exercise Programs for Overcoming Pain and Healing from Injury
Walters, Tom
Cordoza, Glen
Paperback
Dime Dónde Te Duele: La Nueva Ciencia del Dolor Y Cómo Curarlo / Tell Me Where It Hurts
Zoffness, Rachel
Paperback
Mayo Clinic Guide to Pain Relief, 3rd Edition: How to Better Manage Pain and Regain Function
Sutor, Bruce
Gilliam, Wesley P.
Hardcover
Beating Endo: How to Reclaim Your Life from Endometriosis
Orbuch MD, Iris Kerin
Stein Dpt, Amy
Paperback
Rehab Science: Head and Neck: Protocols and Exercise Programs for Overcoming Pain and Healing from Injury
Cordoza, Glen
Walters, Tom
Paperback
Sana Tu Mente, Cura Tu Cuerpo. Un Programa Revolucionario Para Liberarte del Dolor Crónico Y La Ansiedad / Mind Your Body
Sachs, Nicole J.
Paperback
Dr Barbara Inspired 15 Day Gut Cleanse: Transform Your Gut in Just 15 Days! Discover O'Neill's Secrets for Lasting Health
Barbara Oneill, 15 Day Gut Support with
Winfrey, Blessing
Hardcover
Rehab Science: Elbow, Wrist and Hand: Protocols and Exercise Programs for Overcoming Pain and Healing from Injury
Walters, Tom
Cordoza, Glen
Paperback
Yoga for Pelvic Floor and Postpartum Health: An Iyengar Yoga Approach to Pelvic Healing and Integrative Wellness Through Anatomy and Practice
Weisman, Rebecca
Satinsky, Meagen
Paperback
Mending the Body with the Mind: Harnessing Kids' Superpowers to Heal and Stay Healthy
Gottsegen, David
Paperback
Fibromyalgia: A Guide to the Symptoms, Management, and Treatment of Fibromyalgia and Chronic Fatigue
Rose, Jessica
Paperback
The Pain Relief Secret: How to Retrain Your Nervous System, Heal Your Body, and Overcome Chronic Pain
Warren, Sarah
Paperback
Back Sense: A Revolutionary Approach to Halting the Cycle of Chronic Back Pain
Urdang, Michael
Siegel, Ronald D.
Johnson, Douglas R.
Paperback
The FibroManual: A Complete Fibromyalgia Treatment Guide for You and Your Doctor
Liptan, Ginevra
Paperback
Rehab Science: Ankle and Foot: Protocols and Exercise Programs for Overcoming Pain and Healing from Injury
Walters, Tom
Cordoza, Glen
Paperback
Success in Medicine: A Story of Pain, Purpose, Perseverance, and the Hidden Cost of Achievement
Abraham, Bincy P.
Hardcover
Healing Joints and Nerves: Immune Stimulation and the New Science of Regenerative Therapies
Buchheit, Thomas E.
Paperback
The Mediterranean Migraine Diet: A Science-Based Roadmap to Control Symptoms and Transform Brain Health
Wolf, Alicia
Beh, Shin C.
Paperback
Cold Therapy Made Simple: A 5-Step Guide to Using Cold Exposure to Heal Better, Recover Faster, and Live Longer
Peterson, Chris
Hardcover
The Knee Pain Bible: A Self-Care Guide to Eliminating Knee Pain and Returning to the Movements You Love!
Kidawski, Christopher Joseph
Paperback
Practical Solutions for Back Pain Relief: 40 Mind-Body Exercises to Move Better, Feel Better, and Relieve Pain Permanently
Santas, Dana, CSCS E-Ryt
Paperback
Freedom from Pain: Discover Your Body's Power to Overcome Physical Pain
Phillips, Maggie
Levine, Peter
Paperback
Back and Neck Health: Mayo Clinic Guide to Treating and Preventing Back and Neck Pain
Bydon, Mohamad
Paperback
Ageless Painless Tennis: Free Yourself from Pain, Injuries, and Limitations & Unlock Your Athletic Potential
Smith, David Starbuck
Paperback
The Rheumatoid Arthritis Healing Plan: A Holistic Guide and Cookbook for Inflammation Relief
Samson, Caitlin
Paperback
Improve Your Posture in 21 Days: Simple Daily 10-Minute Workouts to Reduce Pain and Stand Taller
Myers, Dominique
Paperback
Psoas Strength and Flexibility: Core Workouts to Increase Mobility, Reduce Injuries and End Back Pain
Ellgen, Pamela
Paperback
Hao Neuro-Acupuncture Restores Life: A New Treatment is Born to Help Patients Suffering from Neurological Disorders
Hao, Jason Jishun
Paperback
Back in Control, 3rd Edition: A Surgeonâ (Tm)S Roadmap Out of Chronic Pain
Hanscom, David, MD
Paperback
The Younger Next Year Back Book: The Whole-Body Plan to Conquer Back Pain Forever
Crowley, Chris
James, Jeremy
Paperback
No Grain, No Pain: A 30-Day Diet for Eliminating the Root Cause of Chronic Pain
Osborne, Peter
Paperback
7 Steps to a Pain-Free Life: How to Rapidly Relieve Back, Neck, and Shoulder Pain
McKenzie, Robin
Kubey, Craig
Paperback
Sciatica Relief Program: Gentle Exercises to Calm Nerve Pain, Restore Mobility, and Return to Activity Safely
Calder, Evan
Paperback
The Back Pain Relief Plan: A 20-Minute Exercise-Based Program to Prevent, Manage, and Ease Pain
Fishman, Ricky
Paperback
Yoga Journal Presents Restorative Yoga for Life: A Relaxing Way to De-Stress, Re-Energize, and Find Balance
Grossman, Gail Boorstein
Paperback
Sciatica Exercises & Home Treatment: Simple, Effective Care For Sciatica and Piriformis Syndrome
Best D. C., George F.
Paperback
Doctor, Why Does My Face Still Ache?: Getting Relief from Persistent Jaw, Ear, Tooth, and Headache Pain
Roistacher, S. L.
Tanenbaum, Donald R.
Paperback
When Sex Hurts: Understanding and Healing Pelvic Pain
Pukall, Caroline
Goldstein, Irwin
Goldstein, Andrew
Paperback
Rebound: Train Your Mind to Bounce Back Stronger from Sports Injuries
Cheadle, Carrie Jackson
Kuzma, Cindy
Paperback
Mind Over Back Pain: A Radically New Approach to the Diagnosis and Treatment of Back Pain
Sarno, John
Paperback
The Concise Book of Trigger Points, Third Edition: A Professional and Self-Help Manual
Niel-Asher, Simeon
Paperback
Understanding Fibromyalgia: A Guide for the confused, frustrated, and newly diagnosed
Dovie, Matthew
Paperback
Shoulder Pain Reset: A Safe Strength and Mobility Plan to Restore Movement and End Shoulder Pain
Calder, Evan
Paperback
The Miracle of Flexibility: A Head-To-Toe Program to Increase Strength, Improve Mobility, and Become Pain Free
Esmonde-White, Miranda
Hardcover
Tu Dolor de Espalda Tiene Solución (Si Sabes Cómo) / Your Back Pain Has a Solution (If You Know How)
Ortega, Juanma
Paperback
Stretching to Stay Young: Simple Workouts to Keep You Flexible, Energized, and Pain Free
Matthews, Jessica
Paperback
The Body Doesn't Lie: A 3-Step Program to End Chronic Pain and Become Positively Radiant
Vlachonis, Vicky
Paperback
Chronic Pain Reset: 30 Days of Activities, Practices, and Skills to Help You Thrive
Hassett, Afton L.
Hardcover
Overcoming Back and Neck Pain: A Proven Program for Recovery and Prevention
Morrone, P. T.
Morrone, Lisa
Paperback
Kinesiology Taping the Essential Step-By-Step Guide: Taping for Sports, Fitness and Daily Life - 160 Conditions and Ailments
Langendoen, John
Sertel, Karin
Paperback
Pain Decoded: Demystifying Pain from Supplements to Surgery and Everything in Between
Hassassian, Sassan
Paperback
The Pain Survival Guide: How to Become Resilient and Reclaim Your Life
Winter, Frits, PhD
Turk, Dennis C., PhD
Paperback
Crooked: Outwitting the Back Pain Industry and Getting on the Road to Recovery
Ramin, Cathryn Jakobson
Paperback
Your Life Pain Free: A Doctor's Guide to Healing from Pain, Strengthening Your Core, and Living the Sport of Life
Richardson, Donald
Paperback
Conquering Your Child's Chronic Pain: A Pediatrician's Guide for Reclaiming a Normal Childhood
Zeltzer, Lonnie K.
Schlank, Christina Blackett
Paperback
Heal Your Frozen Shoulder: An At-Home Rehab Program to End Pain and Regain Range of Motion
Knopf, Karl
Paperback
The Migraine Brain: Your Breakthrough Guide to Fewer Headaches, Better Health
Bernstein, Carolyn
McArdle, Elaine
Paperback
Pain, Power & Pride: Evidence-based Strategies for Living Fully Despite Persistent Pain
Lane, Ian A.
Paperback
Sciatica Solutions: Diagnosis, Treatment, and Cure of Spinal and Piriformis Problems
Fishman, Loren
Ardman, Carol
Paperback
They Can't Find Anything Wrong!: 7 Keys to Understanding, Treating, and Healing Stress Illness
Clarke, David D.
Paperback
Fighting to Survive The Suicide Disease: Pudendal Nerve Entrapment and Neuralgia Disease
V. Rentz, Judy
Paperback
Migraine Journal: A Daily Tracking Journal For Migraines and Chronic Headaches (Trigger Identification + Relief Log)
Press, Wellness Warrior
Paperback
107 Rotator Cuff Exercises: To Build, Protect and Maintain a Healthy Rotator Cuff For Life
Calhoon, Zach
Paperback
Venous And Lymphatic Insufficiency: Reduce Swelling, Support Healthy Circulation, Prevent Complications, and Improve Quality of Life
Sterling, Isaac M.
Paperback
Migraine Warrior: A Daily Tracking Journal For Migraines and Chronic Headaches (Trigger Identification + Relief Log)
Press, Wellness Warrior
Paperback
Daily Pain & Symptom Tracker: A Detailed Pain & Symptom Tracking Journal for Chronic Pain & Illness
Press, Wellness Warrior
Paperback
The Back Pain Bible: A Breakthrough Step-By-Step Self-Treatment Process To End Chronic Back Pain Forever
Kidawski, Christopher J.
Paperback
Foundation: Redefine Your Core, Conquer Back Pain, and Move with Confidence
Goodman, Eric
Park, Peter
Paperback