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612-822-4611
Investigation on Wood of Sesbania Sesban (L.) merr, Fabaceae

Investigation on Wood of Sesbania Sesban (L.) merr, Fabaceae

Paperback

Botany & Horticulture

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ISBN10: 363931770X
ISBN13: 9783639317701
Publisher: Blues Kids Of Amer
Published: Jan 7 2011
Pages: 120
Weight: 0.41
Height: 0.28 Width: 6.00 Depth: 9.00
Language: English
Natural products have served as a major source of drugs from centuries and about half of pharmaceuticals in use today are derived from natural products. Despite the achievements of synthetic chemistry and the advances towards rational drug design, natural products are essential in providing medicinal compounds as starting points for development of synthetic analogues. The present results of the thesis indicate that the methanol extract of S. sesban exhibits central and peripheral analgesic activity through opioid receptors. On preliminary phytochemical screening the methanol extract of S. sesban was found to contain tannins, saponins, alkaloid compounds. Four fractions ME1 to ME4 were isolated by using column chromatography. These fractions were screened for analgesic activity by using hot plate method, acetic acid induced writhing, formalin induced paw licking in mice. Present study reveals that methanol extract of S. sesban has potent analgesic and anti-inflammatory activity and this may be due to presence of acidic functional group.

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Botany & Horticulture