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Detection of Fetal Abnormalities Based on Three Dimensional Nuchal Translucency
Paperback
Series: Springerbriefs in Applied Sciences and Technology
Women's HealthTechnology & Engineering
ISBN13: 9789814021951
Publisher: Springer Pg
Published: Oct 30 2012
Pages: 113
Weight: 0.45
Height: 0.40 Width: 6.00 Depth: 9.00
Language: English
1 Introduction
1.1 Background of Research
1.2 Problem Statement
1.3 Objectives
1.4 Scope of Project
1.5 Contribution of Book
2 Medicine and Engineering Related Researches on the Utility of
Two Dimensional Nuchal Translucency
2.1 Review of Trisomy 21
2.2 History of Trisomy 21 Detection
2.4 Effect of Previous Pregnancies Factor
2.5 Existing Detection Methods of Trisomy 21
2.5.1 Ultrasound
2.5.2 Maternal Serum Markers
2.5.3 Genetic Testing
2.5.4 Summary
2.6 Two Dimensional Nuchal Translucency
2.6.1 Medicine Review and Related Researches
2.6.1.1 Existing Limitation
2.6.2 Engineering Review and Related Researches
2.6.2.1 Summary
2.7 Three Dimensional Ultrasound Applications
2.7.1 Summary
3 Designs and Implementation of Three Dimensional Nuchal Translucency
3.1 Introduction
3.2 Data Acquisition
3.3 DICOM and Clips Storage
3.4 3D NT Reconstruction and Visualization
3.4.1 3D Scanning Acquisitions
3.4.2 3D Volume Rendering
3.4.2.1 Virtual Slider Extraction Designs
3.4.2.2 VTK Widget Event Handling Mechanism
3.5 3D Nuchal Translucency Segmentation
3.5.1 Preprocessing 3D Diffusion
3.5.2 3D Seeded Region-Based Segmentation
3.5.3 3D NT in Vivo Measurement
4 Clinical Tests and Measurements
4.1 Introduction
4.2 Descriptive Analysis
4.3 Intra-Observer Variability
4.4 Level Agreement between Measurements
4.4.1 Paired Sample t-test
4.5 Method Repeatability
4.6 Summary
4.7 Discussion
4.7.1 Advantages and Disadvantages of Early Fetal
Abnormalities Detection
5 Future Improvements
5.1 Conclusions
5.2 Limitations and Recommendations
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