Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Apoptotic studies and phytochemical analyses in the suicide tree

Apoptotic studies and phytochemical analyses in the suicide tree

Nampy, Anagha
Varghese, Vigimol T.
Thoppil, John E.

Paperback

Botany & Horticulture

ISBN10: 6202516127
ISBN13: 9786202516129
Publisher: Lap Lambert Academic Pub
Published: Mar 25 2020
Pages: 68
Weight: 0.25
Height: 0.16 Width: 6.00 Depth: 9.00
Language: English
This book entitled Apoptotic studies and phytochemical analyses in the suicide tree, Cerbera odollam Gaertn. (Apocynaceae) reveals the apoptotic and phytochemical efficacy of a potential medicinal plant. C. odollam is native to India and other parts of southern Asia. The suicide plant, C. odollam has got kernels that contain a digoxin type cardenolide and cardiac toxin Cerberin that blocks the calcium ion channels in heart muscle, disrupting the heartbeat, which may be fatal if consumed. The aqueous solutions of the leaf extracts were assessed for the existence of potential phytochemical constituents. Quantitative preliminary phytochemical analysis was done to reveal total phenolic, flavonoid, terpenoid, and alkaloid content. Cytotoxic studies were carried out using Allium cepa root tip assay and the cell death was determined by Evans blue stain both macroscopically and spectrophotometrically. Cellular abnormalities like induction of binucleate cells, apoptotic fragmentation, ghost cell, giant cell, membrane blebs, sticky metaphase, etc. were observed during cytotoxic evaluation. The study reveals the significant apoptotic/cytotoxic activities of aqueous extracts of C. odollam.

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