Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Phytochemical and Pharmacological Assessment of Pithecellobium dulce

Phytochemical and Pharmacological Assessment of Pithecellobium dulce

Swaminathan, Gomathi
Roy, Anupama

Paperback

Medical Reference

ISBN10: 6209451071
ISBN13: 9786209451072
Publisher: LAP Lambert Academic Publishing
Published: Jan 5 2026
Pages: 64
Weight: 0.22
Height: 0.15 Width: 6.00 Depth: 9.00
Language: English
Pithecellobium dulce (P. dulce), a Fabaceae plant commonly found in tropical regions, is well known for its nutritional and medicinal value. While its antibacterial, anti-inflammatory, antidiabetic, hepatoprotective, antioxidant, and anticancer activities are well documented, its neuroprotective potential remains underexplored. This study evaluates the antioxidant and anti-Alzheimer's activity of a 90% ethanolic leaf extract of P. dulce (EEPD). Phytochemical screening revealed the presence of flavonoids, alkaloids, tannins, terpenoids, steroids, and phenolic compounds. EEPD showed strong free-radical scavenging activity with the lowest IC₅₀ value in the DPPH assay. Fractionation guided by TLC and flash chromatography yielded phenolic-rich fractions, confirmed by LC-MS analysis. In SH-SY5Y neuronal cells, EEPD significantly improved cell viability and demonstrated notable neuroprotective effects, comparable to memantine. These findings highlight the promising antioxidant and neuroprotective potential of P. dulce leaves and support further molecular studies toward plant-based therapies for neurological disorders.

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