Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Gastroretentive Floating Drug Delivery System of Zaleplon Tablets

Gastroretentive Floating Drug Delivery System of Zaleplon Tablets

Swaminathan, Gomathi
Raman, Kannan
Subramani, M.

Paperback

Medical Reference

ISBN10: 6208415233
ISBN13: 9786208415235
Publisher: LAP Lambert Academic Publishing
Published: Nov 26 2024
Pages: 80
Weight: 0.28
Height: 0.19 Width: 6.00 Depth: 9.00
Language: English
Floating Drug Delivery Systems are retained in the stomach for a longer time and assist in improving the oral controlled delivery of drugs that have an absorption window in the particular region of the GI tract as well as for controlling the release of the drug having site-specific absorption limitationZaleplon is a highly effective sedative-hypnotic that was used as a model drug to develop a controlled-release formulation. Zaleplon exhibits pH-dependent solubility. It is more soluble in acidic pH and slightly soluble in neutral or alkaline conditions (intestinal environment). Hence an attempt was made to develop a gastroretentive delivery system Zaleplon which increased the bioavailability of Zaleplon and also reduced the frequency of administration, thereby improving patient compliance and therapeutic efficacy.

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