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Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy
Hardcover
ISBN13: 9783540331766
Publisher: Springer Nature
Published: Oct 15 2007
Pages: 845
Weight: 4.83
Height: 1.65 Width: 7.88 Depth: 9.60
Language: English
This book is divided into 3 parts. Part 1 summarizes the pro-angiogenic factors and anti-angiogenic molecules including their mechanism of action. Part 2 summarizes the preclinical data arising from the experimental evaluation of anti-angiogenic and pro-angiogenic compounds in cell culture and animal models. This will help to elucidate their mechanism of action in different biologic systems and cancer types. Based on this knowledge, clinicians will be able to incorporate these new drugs into the scenario of established therapies and finally improve curative approaches. Part 3 summarizes experimental and clinical studies of combined therapy with anti-angiogenic agents and highlights the challenges related to the appropriate strategies for selection of the patients, study design, and choice of proper end points for preclinical and clinical studies using these agents.
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