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One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays
Hardcover
Series: Springer Theses
Medical ReferenceTechnology & Engineering
ISBN13: 9789811380938
Publisher: Springer Nature
Published: May 28 2019
Pages: 52
Weight: 0.63
Height: 0.25 Width: 6.14 Depth: 9.21
Language: English
In this thesis, the author firstly describes the need and concept of 'partipetting' for pipetting-free HTS platform. It is realized by the one-step pipetting and self-assembly of encoded drug-laden microparticles (DLPs) on the microwells. Next, the technical implementations required for the platform demonstration are described. It includes preparation of encoded DLPs, plastic chip fabrication, andrealization of automated system. Lastly, screening of sequential drug combinations using this platform is demonstrated. This shows the potential of the proposed technology for various applications.
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