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A Novel Method for Predicting Product Properties in Fluidized Bed Spray Granulation

A Novel Method for Predicting Product Properties in Fluidized Bed Spray Granulation

Paperback

Technology & Engineering

ISBN10: 3736975562
ISBN13: 9783736975569
Publisher: Cuvillier
Published: Jan 3 2022
Pages: 208
Weight: 0.75
Height: 0.44 Width: 6.69 Depth: 9.61
Language: English
Fluidized bed spray granulation is a process that facilities particle size enlargement by injecting solids in the form of a suspension, solution or melt. The produced particles are often of high value due to their highly specific, functionalized nature. This work provides a method for utilizing particle-scale simulations method like the coupled Computational Fluid Dynamics-Discrete Element Method (CFD-DEM) to predict the properties of particles produced in scaled-up apparatuses based on laboratory-scale experiments by correlating the conditions that particle experience to the properties they develop. Furthermore, a method for calibrating DEM models of weakly wetted particle systems by utilizing a novel, probabilistic liquid bridge state model is proposed.

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Technology & Engineering