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Nanotechnology Applied to Nutraceuticals: Overcoming Biopharmaceutical Barriers in Chronic Diseases
Hardcover
Medical ReferenceTechnology & EngineeringGeneral Science
ISBN13: 9783032420879
Publisher: Springer
Published: Feb 24 2027
Pages: 472
Language: English
This book provides a comprehensive and critical analysis of the development and application of nutraceuticals and bioactive derivatives, with particular emphasis on their integration into nanopharmaceutical systems to improve therapeutic efficacy, bioavailability, and safety. It examines the evolution from classical pharmacotherapy toward nutraceutical and preventive approaches, the increasingly blurred boundaries between drugs, nutraceuticals, and supplements, and the major biopharmaceutical barriers that limit their clinical effectiveness. Nanotechnology is presented as a key strategy to overcome these challenges, with applications explored in relevant clinical settings, including intestinal dysbiosis, hepatic and renal diseases, metabolic disorders, neuroprotection, and anticancer applications.
The book combines fundamental principles of nanotechnology with an analysis of lipid-based, polymeric, inorganic, and hybrid nanocarrier systems, addressing their design, characterization, biological performance, advantages, and limitations. Evidence from in vitro models, preclinical studies, and available clinical data is integrated to critically assess the potential of nanoformulated versus conventional nutraceuticals and the challenges involved in their clinical translation. Safety considerations, regulatory frameworks, and risk perception are also examined from an international perspective. Overall, this work offers an updated, critical, and translational perspective on nanonutraceuticals and bioactive compounds, providing a valuable resource for researchers, health professionals, postgraduate students, and stakeholders in the biotechnology and pharmaceutical sectors.
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