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Lupus: Molecular and Cellular Pathogenesis

Lupus: Molecular and Cellular Pathogenesis

Hardcover

Series: Contemporary Immunology, Book 7

Medical Reference

ISBN10: 0896035565
ISBN13: 9780896035560
Publisher: Springer Nature
Published: May 4 1999
Pages: 709
Weight: 3.35
Height: 1.90 Width: 7.30 Depth: 10.20
Language: English
Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.

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