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Enterobacteriaceae produttrici di carbapenemasi (CPE)
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ISBN10: 6202325992
ISBN13: 9786202325998
Publisher: Edizioni Sapienza
Published: Jul 29 2025
Pages: 60
Weight: 0.21
Height: 0.14 Width: 6.00 Depth: 9.00
Language: Italian
ISBN13: 9786202325998
Publisher: Edizioni Sapienza
Published: Jul 29 2025
Pages: 60
Weight: 0.21
Height: 0.14 Width: 6.00 Depth: 9.00
Language: Italian
I carbapenemi sono il gruppo più potente di agenti antimicrobici disponibili e sono spesso utilizzati come ultima linea di difesa per il trattamento delle infezioni causate da bacilli Gram-negativi multiresistenti. Le Enterobacteriaceae resistenti ai carbapenemi (CRE) sono ora designate dai Centers for Disease Control and Prevention (CDC) come batteri da incubo. Le infezioni da CRE sono associate a un'elevata mortalità , principalmente a causa del ritardo e dell'estrema limitazione delle opzioni terapeutiche efficaci. Poiché la produzione di carbapenemasi è il principale meccanismo di resistenza ai carbapenemi, la comparsa di Enterobacteriaceae produttrici di carbapenemasi (CPE) è diventata una minaccia sanitaria globale. L'epidemiologia delle CPE è ben definita in Europa, dove sono state condotte diverse indagini epidemiologiche nazionali e multinazionali, mentre i dati provenienti dalle regioni del Nord Africa e del Medio Oriente sono ancora insufficienti. In questa revisione l'autore cerca di stimare la situazione in particolare in Egitto e in altri paesi del Medio Oriente. Questo lavoro fornisce gli ultimi aggiornamenti sull'argomento per quanto riguarda i metodi di rilevamento e le opzioni terapeutiche come principali direzioni per limitare la diffusione di questi superbatteri!
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