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Carbapenemase-produzierende Enterobacteriaceae (CPE)
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ISBN10: 6202325968
ISBN13: 9786202325967
Publisher: Verlag Unser Wissen
Published: Jul 29 2025
Pages: 64
Weight: 0.22
Height: 0.15 Width: 6.00 Depth: 9.00
Language: German
ISBN13: 9786202325967
Publisher: Verlag Unser Wissen
Published: Jul 29 2025
Pages: 64
Weight: 0.22
Height: 0.15 Width: 6.00 Depth: 9.00
Language: German
Carbapeneme sind die wirksamsten verfügbaren antimikrobiellen Wirkstoffe und werden häufig als letzte Option zur Behandlung von Infektionen eingesetzt, die durch multiresistente gramnegative Bazillen verursacht werden. Carbapenem-resistente Enterobacteriaceae (CRE) werden von den Centers for Disease Control and Prevention (CDC) mittlerweile als Albtraum-Bakterien bezeichnet. CRE-Infektionen sind mit einer hohen Sterblichkeitsrate verbunden, die in erster Linie auf die Verzögerung und die äu erst begrenzten wirksamen Behandlungsmöglichkeiten zurückzuführen ist. Da die Produktion von Carbapenemase der Hauptmechanismus der Resistenz gegen Carbapeneme ist, stellt das Auftreten von Carbapenemase-produzierenden Enterobacteriaceae (CPE) eine globale Gesundheitsbedrohung dar. Die Epidemiologie von CPE ist in Europa, wo mehrere nationale und multinationale epidemiologische Erhebungen durchgeführt wurden, gut definiert, während die Daten aus Nordafrika und dem Nahen Osten noch unzureichend sind. In dieser Übersicht versucht der Autor, die Situation insbesondere in Ägypten und anderen Ländern des Nahen Ostens einzuschätzen. Diese Arbeit liefert die neuesten Informationen zu diesem Thema hinsichtlich der Nachweismethoden und Behandlungsmöglichkeiten als wichtigste Ma nahmen zur Eindämmung der Ausbreitung dieser Superbakterien!
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