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Gene Regulation and Therapeutics for Cancer
Hardcover
Medical ReferenceBiologyGenetics
ISBN13: 9781138712423
Publisher: Crc Pr Inc
Published: Mar 22 2021
Pages: 322
Weight: 1.41
Height: 0.75 Width: 6.14 Depth: 9.21
Language: English
Differential gene regulation and targeted therapy are the critical aspects of several cancers. This book covers specific gene regulation and targeted therapies in different malignancies. It offers a comprehensive assessment of the transcriptional dysregulation in cancer, and considers some examples of transcriptional regulators as definitive oncogenic drivers in solid tumors, followed by a brief discussion of transcriptional effectors of the programs they drive, and discusses its specific targets. Most targeted therapeutics developed to date have been directed against a limited set of oncogenic drivers, exemplified by those encoding cell surface or cytoplasmic kinases that function in intracellular signaling cascades.
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