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Gene Regulation and Therapeutics for Cancer
Paperback
Medical ReferenceBiologyGenetics
ISBN13: 9780367541163
Publisher: CRC Press
Published: Sep 15 2022
Pages: 322
Weight: 1.02
Height: 0.69 Width: 6.14 Depth: 9.21
Language: English
Differential gene regulation and targeted therapy are the critical aspects of several cancers. This book covers specific gene regulation and targeted therapies in different malignancies. It offers a comprehensive assessment of the transcriptional dysregulation in cancer, and considers some examples of transcriptional regulators as definitive oncogenic drivers in solid tumors, followed by a brief discussion of transcriptional effectors of the programs they drive, and discusses its specific targets. Most targeted therapeutics developed to date have been directed against a limited set of oncogenic drivers, exemplified by those encoding cell surface or cytoplasmic kinases that function in intracellular signaling cascades.
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