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612-822-4611
Algorithms for Sample Preparation with Microfluidic Lab-on-Chip

Algorithms for Sample Preparation with Microfluidic Lab-on-Chip

Hardcover

Series: Biomedical Engineering

Technology & EngineeringProgramming

ISBN10: 8770220557
ISBN13: 9788770220552
Publisher: River Publishers
Published: Feb 5 2019
Pages: 178
Weight: 0.95
Height: 0.44 Width: 6.14 Depth: 9.21
Language: English

Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design.

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