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One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays
Paperback
Series: Springer Theses
Medical ReferenceTechnology & EngineeringPhysics
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ISBN13: 9789811380969
Publisher: Springer
Published: Aug 14 2020
Pages: 52
Weight: 0.26
Height: 0.16 Width: 6.10 Depth: 9.25
Language: English
In this thesis, the author firstly describes the need and concept of 'partipetting' for pipetting-free HTS platform. It is realized by the one-step pipetting and self-assembly of encoded drug-laden microparticles (DLPs) on the microwells. Next, the technical implementations required for the platform demonstration are described. It includes preparation of encoded DLPs, plastic chip fabrication, andrealization of automated system. Lastly, screening of sequential drug combinations using this platform is demonstrated. This shows the potential of the proposed technology for various applications.
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