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Vaccine Adjuvants

Vaccine Adjuvants

Paperback

Series: Infectious Disease

Medical Reference

ISBN10: 1617372404
ISBN13: 9781617372407
Publisher: Springer Nature
Published: Dec 9 2010
Pages: 284
Weight: 0.97
Height: 0.67 Width: 6.00 Depth: 9.00
Language: English
A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.

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Medical Reference