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612-822-4611
Vitamin D

Vitamin D

Paperback

Medical Reference

ISBN10: 6209635881
ISBN13: 9786209635885
Publisher: Our Knowledge Publishing
Published: Feb 19 2026
Pages: 84
Weight: 0.27
Height: 0.20 Width: 6.00 Depth: 9.00
Language: English
People cover most of their vitamin D requirements through exposure to sunlight, as only a few foods, such as wild salmon, are naturally rich in vitamin D. UVB radiation is absorbed through the skin and causes the conversion of 7-dehydrocholesterol to previtamin D3. This is converted into vitamin D3, which is transported to the liver, where it is hydroxylated into 25-hydroxyvitamin D3. The measurement of 25(OH) D3 concentrations is crucial for classifying vitamin D status, which, however, is not yet uniformly defined worldwide. 25(OH) D3 is then transported to the kidneys, where it is hydroxylated to 1,25-dihydroxyvitamin D3. This is the biologically active form and is therefore responsible for calcium homeostasis. Around one billion people are currently affected by vitamin D deficiency. This causes rickets in children and osteomalacia in adults. However, we now know that vitamin D deficiency is also responsible for many extraskeletal consequences, such as an increased risk of developing cancer and multiple sclerosis or suffering from cardiovascular disease.

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Medical Reference