Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Vitamin D Status in Asthmatic Children

Vitamin D Status in Asthmatic Children

Khalsi, Fatma

Paperback

Medical Reference

ISBN10: 6207673255
ISBN13: 9786207673254
Publisher: Our Knowledge Publishing
Published: Jun 19 2024
Pages: 52
Weight: 0.20
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
Asthma in children is the most common respiratory disease worldwide. It is a major cause of morbidity and mortality. An accurate assessment of its prevalence has been hampered by the heterogeneity of asthma definitions. It has been described that vitamin D possesses an immunomodulatory effect via its receptor (VDR) and 1-alpha-hydroxylase, which are present in T and B lymphocytes, macrophages and antigen-presenting cells. Thus, 25 hydroxy-vitamin D (25 OH D) reduces the proliferation of T lymphocytes (particularly Thelper-1 [Th1] and Th17 lymphocytes) and the production of certain pro-inflammatory cytokines (particularly Il-2, Il-6 and IFN-γ), and it has also been described that the vitamin reduces mainly viral respiratory infections and improves lung function. The interaction between asthma and vitamin D has been studied over the past two decades. This interaction is multi-faceted and has potential clinical implications for asthmatic patients, affecting disease severity, control and prognosis.

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