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Viruses and the Nucleus

Viruses and the Nucleus

Hardcover

Biology

ISBN10: 0470851120
ISBN13: 9780470851128
Publisher: John Wiley & Sons
Published: Jun 20 2006
Pages: 296
Weight: 1.54
Height: 0.88 Width: 6.84 Depth: 9.66
Language: English
Viruses have limited genome-coding capacities and must therefore rely on their host cells to facilitate every step of the infection cycle from the replication of their genomes, transcription and translation of mRNAs to virus assembly. Aimed at virologists and cell biologists Viruses and the Nucleus provides a comprehensive and cohesive overview of this fascinating and fast moving field. It compares and contrasts the ways in which DNA viruses, retroviruses and RNA viruses interact with the host cell nucleus to bring about replication and how they subvert the host cell function to proliferate and survive.

Written by a team of leading experts in the field, this multi-authored text begins with an introduction to the key nuclear process that effect virus biology including cell cycle, transcription, splicing and protein trafficking. It then goes on to explore the advances that have been made in understanding the ways in which specific viruses interact with nuclear sub-structures such as the nucleolus and ND10s, and the implications this interrelationship has for the cell cycle as a whole.

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