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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Untranslated Gene Regions and Other Non-Coding Elements: Regulation of Eukaryotic Gene Expression

Untranslated Gene Regions and Other Non-Coding Elements: Regulation of Eukaryotic Gene Expression

Barrett, Lucy W.
Fletcher, Sue
Wilton, Steve D.

Paperback

Series: Springerbriefs in Biochemistry and Molecular Biology

Medical ReferenceBotany & HorticultureChemistry

ISBN10: 3034806787
ISBN13: 9783034806787
Publisher: Springer
Published: Jul 9 2013
Pages: 56
Weight: 0.30
Height: 0.20 Width: 6.00 Depth: 8.90
Language: English
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as junk DNA, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5' and 3' untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.​

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