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Trophoblasts: Methods and Protocols

Trophoblasts: Methods and Protocols

Hardcover

Series: Methods in Molecular Biology, Book 2728

Biology

ISBN10: 1071634941
ISBN13: 9781071634943
Publisher: Humana Pr
Published: Nov 30 2023
Pages: 248
Weight: 1.48
Height: 0.63 Width: 7.00 Depth: 10.00
Language: English

This volume explores the latest approaches used to assess trophoblast angiogenesis, transport function, cellular respirations, migration, and invasion. The chapters in this book cover topics such as various methods to study and manipulate primary trophoblast cells; strategies using liposomes to deliver biomolecules to trophoblasts; in vitro models of the placenta that emulate the cellular interactions in the 3D uterine environment; and models exploring heterogenous cell types and 3D-organoid structures that represent cell-to-cell interactions in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Trophoblasts: Methods and Protocols is a valuable resource that will help researchers better understand the function of the placenta and its complex contribution to maternal health and fetal development, and also provide greater insights to the area of study known as the developmental origins of health and diseases (DoHaD).

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Biology