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Translating Molecular Biomarkers Into Clinical Assays: Techniques and Applications

Translating Molecular Biomarkers Into Clinical Assays: Techniques and Applications

Hardcover

Series: Aaps Advances in the Pharmaceutical Sciences, Book 21

Medical ReferenceChemistry

ISBN10: 3319407929
ISBN13: 9783319407920
Publisher: Springer
Published: Aug 30 2016
Pages: 212
Weight: 1.10
Height: 0.56 Width: 6.14 Depth: 9.21
Language: English
This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.

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