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Toxicity and Autophagy in Neurodegenerative Disorders
Hardcover
Series: Current Topics in Neurotoxicity, Book 9
ISBN13: 9783319139388
Publisher: Springer
Published: May 19 2015
Pages: 268
Weight: 1.27
Height: 0.69 Width: 6.14 Depth: 9.21
Language: English
Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.
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