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The Inflammasome: Methods and Protocols

The Inflammasome: Methods and Protocols

Paperback

Series: Methods in Molecular Biology, Book 2459

Medical Reference

ISBN10: 1071621467
ISBN13: 9781071621462
Publisher: Humana Pr
Published: Feb 27 2023
Pages: 180
Weight: 0.75
Height: 0.41 Width: 7.00 Depth: 10.00
Language: English

This volume provides inflammasome instructions and tips to study different aspects of inflammasome biology. Chapters guide readers through how to assess canonical and non-canonical inflammasome activation, in vitro immune and non-immune cells, whole blood, biochemical assays to evaluate ASC oligomerization, gasdermin D cleavage, and mapping phosphorylated residues of NLRP3. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

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Abdul-Sater, Ali A.

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Medical Reference