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Targeted Therapeutics in Melanoma
Hardcover
Series: Current Clinical Oncology
ISBN13: 9781617794063
Publisher: Springer Nature
Published: Dec 14 2011
Pages: 378
Weight: 1.45
Height: 0.90 Width: 6.10 Depth: 9.00
Language: English
Molecular targets and subtypes in melanoma.- Melanoma genomics.- Predictive biomarkers as a guide to future therapy selection in melanoma.- KIT as a therapeutic target for melanoma.- Targeted inhibition of B-Raf.- The notch and B-catenin pathways.- STAT3 and Src signaling in melanoma.- Targeting the mTOR, PI3K and AKT pathways in melanoma.- Targeting apoptotic pathways in melanoma.- Anti-angiogenesis therapy in melanoma.- Melanoma antigens recognized by T lymphocytes.- Melanoma vaccines.- Adoptive cell therapy for the treatment of metastatic melanoma.- Anti-CTLA-4 monolonal antibodies.- Anti-PD-1 and Anti-B7-H1/PD-L1 monoclonal antibodies.- Treatment of melanoma with agonist immune co-stimulatory agents.- Novel cytokines for immunotherapy of melanoma.- Modulating the tumor microenvironment.
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