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Trim/Rbcc Proteins

Trim/Rbcc Proteins

Paperback

Series: Advances in Experimental Medicine and Biology, Book 770

Medical ReferenceBiologyChemistry

ISBN10: 1493946609
ISBN13: 9781493946600
Publisher: Springer
Published: Oct 22 2016
Pages: 145
Weight: 0.67
Height: 0.36 Width: 7.00 Depth: 10.00
Language: English
The genomic 'golden age' has delivered the sequence of numerous novel genes while leaving us with many unanswered questions about their function. This is particularly true for gene families as, often, members are annotated based on homology rather than function. The tripartite motif family belonged to this category, although, during the last few years, the field boosted an important wealth of biochemical, cellular and physiological breakthrough data. In the first part of this book, we attempt to offer an overview of state-of-the-art basic findings on the tripartite motif (TRIM, also known as RBCC) family members and to deal in the second part with their relevant and growing physiological and pathological roles.

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