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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Translating Molecules Into Medicines: Cross-Functional Integration at the Drug Discovery-Development Interface

Translating Molecules Into Medicines: Cross-Functional Integration at the Drug Discovery-Development Interface

Bhattachar, Shobha N.
Morrison, John S.
Mudra, Daniel R.

Paperback

Series: Aaps Advances in the Pharmaceutical Sciences, Book 25

Medical ReferenceChemistry

ISBN10: 3319843036
ISBN13: 9783319843032
Publisher: Springer
Published: Jul 20 2018
Pages: 461
Weight: 1.49
Height: 0.98 Width: 6.14 Depth: 9.21
Language: English
Tackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understanding of diseases, drug discovery, and drug development. Laying out the detailed trends from various fields, different chapters are dedicated to target engagement, toxicological safety assessments, and the compelling relationship of optimizing early clinical studies with design strategies. The book also highlights the importance of balancing the three pillars: sufficient efficacy, acceptable safety and appropriate pharmacokinetics, all of which are crucial to successful efforts in discovery and development. With discussions regarding the combined approaches of molecular research, personalized medicine, pre-clinical and clinical development, as well as targeted therapies-this compendium is a flexible fit, perfect for professionals in the pharmaceutical industry and related academic fields.

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