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Transforming Growth Factor-Beta in Cancer Therapy, Volume I: Basic and Clinical Biology

Transforming Growth Factor-Beta in Cancer Therapy, Volume I: Basic and Clinical Biology

Paperback

Series: Cancer Drug Discovery & Development

Medical ReferenceBiology

ISBN10: 161737735X
ISBN13: 9781617377358
Publisher: Humana
Published: Nov 19 2010
Pages: 735
Weight: 2.85
Height: 1.51 Width: 7.00 Depth: 10.00
Language: English
Transforming Growth Factor-jl in Cancer Therapy, Volume I: Basicand Clinical Biology The present volume brings together a wealth of information that is fundamental to understanding the roleofTGF- in the pathogenesis, prevention, and treatment of cancer. It is not even 25 years sinceTGF- was first isolated and characterized as a dimeric pep- tide from both human and bovine sources (1-3), but the entire fieldofTGF- research has grown and expanded so that it is now a central theme in all of cell biology. There is almost no tissue or organ in the mammalian body in whichTGF- does not playa central role in embryonic differentiation or in adult function, and furthermore, malfunction of the normal physiologyofTGF- can have disastrous consequences in almost all ofthese sites. Therefore, the present comprehensive review of so many aspects ofTGF- function is a most welcome attempt to bring together a huge body of experimental data that is of the utmost importance in the field of oncology.

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