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Toxicogenomics in Predictive Carcinogenicity

Toxicogenomics in Predictive Carcinogenicity

Hardcover

Series: Issues in Toxicology, Book 28

Medical ReferenceGenetics

Currently unavailable to order

ISBN10: 1782621628
ISBN13: 9781782621621
Publisher: Royal Society Of Chemistry
Published: Jul 26 2016
Pages: 524
Weight: 2.00
Height: 1.30 Width: 6.40 Depth: 9.30
Language: English

Toxicogenomics in Predictive Carcinogenicity describes toxicogenomics methods in predictive carcinogenicity testing, mode of action and safety evaluation, and cancer risk assessment. It illustrates these methods using case studies that have yielded significant new information on compounds and classes of compounds that have proven difficult to evaluate using conventional methods alone. This book additionally covers current and potential toxicogenomic research using stem cells as well as new bioinformatics methods for drug discovery and environmental toxicology.The information is needed because it has not previously been available. With the increasing complexity of research in mode of action investigations it is important to gain a better understand of approaches to data integration and health risk assessment. Furthermore, it is essential to consider how novel test systems and newer methods and approaches may be used in future to gain a better understanding of mechanisms. The proposed publication will provide details of chemical case studies not available in previous volumes and will demonstrate how various data is assembled and integrated to arrive at an informed assessment of chemical safety and human health risk. It will be the most current volume which comprehensively covers the subject. This publication is an indispensable tool for postgraduates, academics and industrialists working in biochemistry, genomics, carcinogenesis, pathology, pharmaceuticals, food technology, bioinformatics, risk assessment and environmental toxicology.

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