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Toll-Like Receptors: Methods and Protocols

Toll-Like Receptors: Methods and Protocols

Paperback

Series: Methods in Molecular Biology, Book 517

Medical ReferenceChemistry

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ISBN10: 1617379425
ISBN13: 9781617379420
Publisher: Springer Pg
Published: Jan 26 2011
Pages: 376
Language: English

In addition to their invaluable role in the fight against infection, Toll-Like Receptors (TLRs) in an under- or over-active state can lead to the pathogenesis of disease, making these receptors a key focal point for many research laboratories. In Toll-Like Receptors: Methods and Protocols, experts in the field contribute techniques currently used to study TLRs, their downstream signalling pathways, and their role in the pathogenesis of disease, with sections examining TLR expression and the application of genetic techniques and microarray analysis to TLR research. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include brief introductions to the topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and Notes sections highlighting tips on troubleshooting and avoiding known pitfalls.

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