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Technical Aspects of Toxicological Immunohistochemistry: System Specific Biomarkers

Technical Aspects of Toxicological Immunohistochemistry: System Specific Biomarkers

Paperback

Medical ReferenceBiology

ISBN10: 1493979655
ISBN13: 9781493979653
Publisher: Springer Nature
Published: Mar 27 2019
Pages: 231
Weight: 0.76
Height: 0.51 Width: 6.14 Depth: 9.21
Language: English
This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. Eleven comprehensive chapters provide pathologists and researchers in various sub-disciplines of toxicology with a comprehensive review of the methods and approaches for immunohistochemical staining in various target tissues. It explores the tissue-antigen and antibody-specific problems that may be encountered during the staining procedures and provide potential avenues for resolving various methodological issues. Special attention is paid to the latest enhancement procedures for antigen retrieval and visualization as well as image analysis and antigen quantification. Written by leading researchers in toxicology and pathology, this book is a significant resource for toxicologists and pathologists working with rodents, monkeys and aquatic animal tissues.

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