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Tandem Repeats in Genes, Proteins, and Disease: Methods and Protocols
Hardcover
Series: Methods in Molecular Biology, Book 1017
ISBN13: 9781627034371
Publisher: Springer Nature
Published: May 30 2013
Pages: 258
Weight: 1.45
Height: 0.90 Width: 7.20 Depth: 10.10
Language: English
1. Longitudinal Imaging and Analysis of Neurons Expressing Polyglutamine-Expanded Proteins
Andrey S. Tsvetkov, D. Michael Ando & Steven Finkbeiner
2. Atomic Force Microscopy Assays for Evaluating Polyglutamine Aggregation in Solution and on Surfaces
Kathleen A. Burke and Justin Legleiter
3. Morphometric Analysis of Huntington's Disease Neurodegeneration in Drosophila
Wan Song, Marianne R. Smith, Adeela Syed, Tamas Lukacsovich, Brett A. Barbaro, Judith Purcell, Doug J. Bornemann, John Burke and J. Lawrence Marsh
4. Size Analysis of Polyglutamine Protein Aggregates using Fluorescence Detection in an Analytical UltracentrifugeSaskia Polling, Danny M. Hatters, and Yee-Foong Mok
5. A Method for the Incremental Expansion of Polyglutamine Repeats in Recombinant Proteins
Amy L. Robertson and Stephen P. Bottomley
6. Pulse Shape Analysis (PulSA) to Track Protein Translocalization in Cells by Flow Cytometry: Applications for Polyglutamine Aggregation
Yasmin M. Ramdzan, Rebecca Wood, Danny M. Hatters
7. Characterizing Social Behavior in Genetically Targeted Mouse Models of Brain Disorders
Emma L. Burrows and Anthony J. Hannan
8. PCR Amplification and Sequence Analysis of GC-rich Sequences: Aristaless-Related Homeobox Example
Tan M.H., Gécz J., Shoubridge C.
9. Challenges of sticky Co-Immunoprecipitation; Polyalanine Tract Protein-Protein Interactions
Mattiske T.R., Tan M.H., Gécz J. and Shoubridge C.
10. Molecular Pathology of Polyalanine Expansion Disorders-new
Perspectives from Mouse Models
James N Hughes and Paul Q Thomas
11. Yeast as a Platform to Explore Polyglutamine Toxicity and Aggregation
Martin L. Duennwald
12. Immunobased Detection Assays to Quantify Distinct Mutant Huntingtin Conformations in Biological Samples
Gregor P. Lotz and Andreas Weiss
13. Modeling and Analysis of Repeat RNA Toxicity in Drosophila
Samaraweera, S.E. , O'Keefe, L.V. , van Eyk, C.L. , Lawlor, K.T., Humphreys D.T., Suter, C.M. and Richards, R.I.
14. Analyzing Modifiers of Protein Aggregation in C. elegans by Native Agarose Gel Electrophoresis
Mats Holmberg, Ellen A.A. Nollen
15. Kinetic Analysis of Aggregation Data
Regina M. Murphy
16. A Bioinformatics Method for Identifying Q/N-rich Prion-like Domains in Proteins
Eric D. Ross, Kyle S. MacLea, Charles Anderson, and Asa Ben-Hur
17. Detecting Soluble PolyQ Oligomers and Investigating their Impact on Living Cells using Split-GFP
Patrick Lajoie and Erik Lee Snapp
18. Cell Biological Approaches To Investigate Polyglutamine-Expanded AR Metabolism
Lori J. Cooper and Diane E. Merry
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