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Synthetic DNA Delivery Systems
Hardcover
Series: Biotechnology Intelligence Unit, Book 7
BiologyChemistryLawns, Trees, & Shrubs
ISBN13: 9780306477010
Publisher: Springer Nature
Published: Sep 30 2003
Pages: 135
Weight: 0.81
Height: 0.57 Width: 6.00 Depth: 9.50
Language: English
DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function.
Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest.
Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers are discussed. Targeted delivery to organelles, tumor cells and dendritic cells comprise an important topic.
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