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Studies on Retinal and Choroidal Disorders: Oxidative Stress in Applied Basic Research and Clinical Practice

Studies on Retinal and Choroidal Disorders: Oxidative Stress in Applied Basic Research and Clinical Practice

Hardcover

Series: Oxidative Stress in Applied Basic Research and Clinical Prac

Medical ReferenceBiology

ISBN10: 1617796050
ISBN13: 9781617796050
Publisher: Springer Nature
Published: Feb 17 2012
Pages: 644
Weight: 2.33
Height: 1.60 Width: 6.10 Depth: 9.20
Language: English

Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. It examines the anti-apoptotic activity of α-crystallins in the presence of glutathione, oxidative stress in the mitochondria and endoplasmic reticulum, the role of iron in retinal disease, the mechanisms of pathological VEGF expression, NAPDH oxidase mechanisms, and Hepatocyte Growth Factor in oxidative stress in the retina.

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