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Statistical Human Genetics: Methods and Protocols
Paperback
Series: Methods in Molecular Biology, Book 850
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ISBN13: 9781493958955
Publisher: Humana
Published: Aug 23 2016
Pages: 564
Weight: 2.18
Height: 1.17 Width: 7.01 Depth: 10.00
Language: English
1. Genetic terminology
2. Identification of genotype errors
3. Detecting pedigree relationship errors
4. Identifying cryptic relationships
5. Estimating allele frequencies
6. Testing departure from Hardy-Weinberg proportions
7. Estimating disequilibrium coefficients
8. Detecting familial aggregation
9. Estimating heritability from twin studies
10. Estimating heritability from nuclear family and pedigree data
11. Correcting for ascertainment
12. Segregation analysis using the unified model
13. Design considerations for genetic linkage and association studies
14. Model-based linkage analysis of a quantitative trait
15. Model-based linkage analysis of a binary trait
16. Model-free linkage analysis of a quantitative trait
17. Model-free linkage analysis of a binary trait
18. Single marker association analysis for unrelated samples
19. Single marker family-based association analysis conditional on parental information
20. Single marker family-based association analysis not conditional on parental information
21. Allowing for population stratification in association analysis
22. Haplotype inference
23. Multi-SNP haplotype analysis methods for association analysis
24. Detecting rare variants
25. The analysis of ethnic mixtures
26. Identifying gene interaction networks
27. Structural equation modeling
28. Genotype calling for the Affymetrix platform
29. Genotype calling for the Illumina platform
30. Comparison of requirements and capabilities of major multipurpose software packages
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