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Some Drugs and Herbal Medicines: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
Paperback
Series: IARC Monographs on the Evaluation of the Carcinogenic Risks, Book 76
Medical ReferencePlant Based Remedies
ISBN13: 9789283201465
Publisher: World Health Organization
Published: Jul 18 2016
Pages: 434
Weight: 3.10
Height: 0.90 Width: 9.10 Depth: 12.00
Language: English
The IARC Monographs Working Group relied mainly on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension).
Other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): Aloe vera whole leaf extract, goldenseal root powder, Ginkgo biloba leaf extract, kava extract, and pulegone. In view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans.
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