Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Sirtuin Biology in Endocrinology and Metabolic Disease

Sirtuin Biology in Endocrinology and Metabolic Disease

Welch, Shay

Hardcover

Medical Reference

ISBN13: 9798887404554
Publisher: American Medical Publishers
Published: Sep 26 2023
Pages: 248
Weight: 1.92
Height: 0.63 Width: 8.50 Depth: 11.00
Language: English
Sirtuins refer to a class of signaling proteins involved in metabolic regulation. They are members of the class III family of NAD-dependent histone deacetylases (HDAC). They are involved in a variety of physiological processes ranging from metabolism and endocrine function control to immune coordination and cellular responses to stress. Sirtuin-1 (SIRT1) plays an important role in epigenetics, immunology, and endocrinology. SIRT1's diverse roles include energy sensing metabolic homeostasis regulation, and deacetylation of histone and non-histone proteins in numerous tissues. It also facilitates neuro-endocrine regulation through hypothalamus-pituitary axis stimulation, and synthesis and maintenance of reproductive hormones via steroidogenesis. Some of the other functions involve maintenance of innate and adaptive immune systems via T and B cell maturation regulation, chronic inflammation, and autoimmune diseases. This book provides significant information of sirtuin biology as well as its importance in endocrinology and metabolic disease. It will provide comprehensive knowledge to the readers.

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