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Single-Domain Antibodies: Methods and Protocols

Single-Domain Antibodies: Methods and Protocols

Paperback

Series: Methods in Molecular Biology, Book 2446

BiologyGeneral Science

ISBN10: 1071620770
ISBN13: 9781071620779
Publisher: Humana
Published: Feb 15 2022
Pages: 612
Weight: 2.37
Height: 1.27 Width: 7.00 Depth: 10.00
Language: English

This volume covers current and emerging techniques for studying single-domain antibodies (sdAbs). Chapters guide readers through the biology and immunology of sdAbs in camelids and sharks, isolation of sdAbs, protein engineering approaches to optimize the solubility, stability, valency and antigen binding affinity of sdAbs, and specialized applications of sdAbs. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

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Hussack, Greg

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Biology