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Sickle cell anemia

Sickle cell anemia

Paperback

Medical Reference

ISBN10: 6209575277
ISBN13: 9786209575273
Publisher: LAP Lambert Academic Publishing
Published: Feb 6 2026
Pages: 52
Weight: 0.18
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
Sickle cell anemia is a hereditary blood disorder caused by a mutation in the β-globin gene, leading to formation of abnormal hemoglobin called HbS.Under low oxygen conditions, HbS polymerizes, causing red blood cells to become sickle-shaped, rigid, and fragile.These abnormal cells have a short lifespan (10-20 days) and can block small blood vessels.Key features: Chronic hemolytic anemia. Painful vaso-occlusive crises. Recurrent infections (due to functional asplenia). Delayed growth and organ damage (spleen, kidneys, lungs, brain).

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Rawlani, Sudhir

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Medical Reference