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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Mauvais-Jarvis, Franck

Paperback

Series: Advances in Experimental Medicine and Biology, Book 1043

Medical Reference

ISBN10: 3319888978
ISBN13: 9783319888972
Publisher: Springer Nature
Published: Jun 4 2019
Pages: 627
Weight: 1.98
Height: 1.31 Width: 6.14 Depth: 9.21
Language: English
The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on Sex and gender factors affecting metabolic homeostasis, diabetes and obesity to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases.
There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence boththe development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

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