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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Self-Assembled Molecules - New Kind of Protein Ligands: Supramolecular Ligands

Self-Assembled Molecules - New Kind of Protein Ligands: Supramolecular Ligands

Irena Roterman
Leszek Konieczny

Paperback

Medical Reference

ISBN10: 1013268962
ISBN13: 9781013268960
Publisher: Saint Philip Street Pr
Published: Oct 8 2020
Pages: 146
Weight: 0.78
Height: 0.31 Width: 8.50 Depth: 11.00
Language: English
The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but naturally irreversible complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book.

This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

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