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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Self and Nonself

Self and Nonself

López-Larrea, Carlos

Hardcover

Series: Advances in Experimental Medicine and Biology, Book 738

Medical Reference

ISBN10: 1461416795
ISBN13: 9781461416791
Publisher: Springer
Published: Jan 30 2012
Pages: 320
Weight: 1.70
Height: 0.90 Width: 7.10 Depth: 10.30
Language: English
In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture Immunological Recognition of Self emphasizing the central argument of immunological tolerance in How does the vertebrate organism recognize self from nonself in this the immunological sense--and how did the capacity evolve. The concept of self is linked to the concept of biological self identity. All organisms, from bacteria to higher animals, possess recognition systems to defend themselves from nonself. Even in the context of the limited number of metazoan phyla that have been studied in detail, we can now describe many of the alternative mechanism of immune recognition that have emerged at varying points in phylogeny. Two different arms--the innate and adaptive immune system--have emerged at different moments in evolution, and they are conceptually different. The ultimate goals of immune biology include reconstructing the molecular networks underlying immune processes.

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