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Resistance to Tyrosine Kinase Inhibitors
Hardcover
Series: Resistance to Targeted Anti-Cancer Therapeutics
ISBN13: 9783319460901
Publisher: Springer Nature
Published: Nov 14 2016
Pages: 188
Weight: 1.02
Height: 0.50 Width: 6.14 Depth: 9.21
Language: English
The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.
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