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Rekonstruktsiya Uretry I Trakhei Krolika Zhivym Ekvivalentom Kozhi
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ISBN10: 3659479454
ISBN13: 9783659479458
Publisher: Lap Lambert Academic Pub
Published: Apr 25 2014
Pages: 144
Weight: 0.49
Height: 0.34 Width: 6.00 Depth: 9.00
Language: Russian
ISBN13: 9783659479458
Publisher: Lap Lambert Academic Pub
Published: Apr 25 2014
Pages: 144
Weight: 0.49
Height: 0.34 Width: 6.00 Depth: 9.00
Language: Russian
K nastoyashchemu momentu nakopilos' znachitel'noe kolichestvo dannykh, demanstriruyushchikh, chto v opredelennykh usloviyakh tkanespetsifichnye stvolovye kletki mogut proyavlyat' znachitel'nuyu fenotipicheskuyu plastichnost' i eto pozvolyaet avtoram govorit' o vozmozhnosti transdifferentsirovki etikh kletok. My predpolagaem, chto fenomen plastichnosti mozhet byt' ispol'zovan v tkanevoy inzhenerii i kletochnykh tekhnologiyakh kak podkhod dlya polucheniya kletok i kletochnykh konstruktsiy, neobkhodimykh dlya vosstanovleniya struktur i/ili funktsiy tkaney i organov. Razvitie dannogo napravleniya regenerativnoy meditsiny pozvolit reshit' takuyu aktual'nuyu problemu, kak defitsit sobstvennykh tkaney patsienta, kotoryy na segodnyashniy den' yavlyaetsya prichinoy znachitel'nogo kolichestva neudach rekonstruktivnykh operatsiy. S uchetom izlozhennogo byl issledovan zhivoy ekvivalent kozhi, kak al'ternativnyy istochnik plasticheskogo materiala dlya zakrytiya polnosloynykh epitelio-stromal'nykh povrezhdeniy uretry. Na primere vosstanovleniya uretry laboratornykh krolikov v rabote issledovany issledovana vozmozhnost' transdifferentsirovki epidermal'nykh keratinotsitov v sostave trekhmernykh tkanevykh konstruktsiy v modeli in vivo.
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