Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Role of Capsaicin in Oxidative Stress and Cancer Diet & Cancer 3

Role of Capsaicin in Oxidative Stress and Cancer Diet & Cancer 3

Srivastava, Sanjay K.

Hardcover

Series: Diet and Cancer, Book 3

Medical ReferenceBiology

ISBN10: 9400763166
ISBN13: 9789400763166
Publisher: Springer Nature
Published: May 7 2013
Pages: 178
Weight: 0.95
Height: 0.50 Width: 6.00 Depth: 9.20
Language: English
This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.

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