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Reviews of Physiology, Biochemistry and Pharmacology

Reviews of Physiology, Biochemistry and Pharmacology

Paperback

Series: Reviews of Physiology, Biochemistry and Pharmacology, Book 144

Medical ReferenceAnatomy & Physiology

ISBN10: 3662310074
ISBN13: 9783662310076
Publisher: Springer Nature
Published: Apr 18 2014
Pages: 227
Weight: 0.74
Height: 0.50 Width: 6.14 Depth: 9.21
Language: English
In this volume of Reviews there are three outstanding articles, one on phspholipase D, an enzyme that is widely distributed in bacteria, protozoa, fungi, plants and animals. Phospholipase D carries out a transphosphatidylation reaction, which is unique to this enzyme. This review is focussed on mammalian PLDs. The second review deals with endotoxin tolerance, the term which describes the phenomenon that immune responses and metabolic changes are mitigated after repeated LPS administration. The third article summarizes the current knowledge relevant to understanding the molecular basis of GPCR function and focusses on the underlying mechanisms of GPCR malfunctions responsible for diferent human diseases.

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